TahoeDive: Tahoe Therapeutics partners with Keplogic to launch the Tahoe-100M dataset on Kepler AI

The strategic partnership will allow scientists from around the world to conduct complex bioinformatics analysis on the rich Tahoe-100M dataset with natural language.‍

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A new partnership to accelerate biological insights

Today we’re excited to unveil TahoeDive, a joint product from Tahoe Therapeutics and the Kepler AI platform from Keplogic. TahoeDive brings the power of Tahoe’s landmark Tahoe‑100M single‑cell perturbation atlas directly into Kepler AI’s enterprise‑grade bioinformatics AI agent platform, letting every scientist ask and answer complex questions in plain English—no code required.

What TahoeDive can do

• Natural‑language queries over 100 million single‑cell transcriptomes and derivative datasets
• Automated code generation, analysis, and visualization that previously demanded a team of bioinformaticians
• Context‑aware reasoning that weaves in relevant scientific literature and your own data files
• Scalable compute & secure data access delivered through Kepler’s managed environment

In early tests, Tahoe’s scientists reproduced their recent discovery of novel immunomodulators in minutes with TahoeDive—work that originally took days of bespoke analysis.

About Tahoe Therapeutics

Tahoe Therapeutics is building the next generation of functional genomics platforms to map cell biology at unprecedented scale. Their flagship dataset, Tahoe‑100M, contains more than 100 million single‑cell profiles across 50 cancer cell lines and 1,100 small‑molecule perturbations. By open‑sourcing this resource—downloaded 45 k+ times to date—Tahoe is catalyzing advances in systems biology, drug discovery, and precision medicine.

Our vision at Keplogic

At Keplogic we’re building Kepler AI—enterprise-grade bioinformatics agents. Kepler turns scattered, context‑heavy biotech data into instant insights, enabling wet‑lab scientists to analyze experiments themselves and bioinformaticians to work 10x faster with less data wrangling

Kepler integrates with any data source—S3, Benchling, databases, cloud drives—and operates like a seasoned scientist, reading papers, retaining context, and asking follow‑up questions.

Try TahoeDive today

TahoeDive is currently in open beta, and we’re eager to hear your feedback.

👉 Request access: https://www.tahoebio.ai/tahoedive
✉️ Questions or a dataset of your own? Email us at hello@keplogic.com

Let’s accelerate discovery—together.